Selected Publications

Check all our publications on Google Scholars.

Peptide design and studying

Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites

Parisa Hosseinzadeh, Paris Watson†, Timothy W. Craven†, Xinting Li†, Stephen A. Rettie†,  Fátima Pardo-Avila, Asim K. Bera, Vikram Khipple Mulligan, Peilong Lu, Alexander S. Ford, Brian D. Weitzner, Lance J. Stewart, Adam P. Moyer, Maddalena Di Piazza, Joshua G. Whalen, Per Jr. Greisen, David W. Christianson, David Baker; Nature Communications 2021 (Article)

 

 

 

Comprehensive computational design of ordered peptide macrocycles

Parisa Hosseinzadeh*, Gaurav Bhardwaj*, Vikram Khipple Mulligan*, Matthew D. Shortridge, Timothy W. Craven, Fátima Pardo-Avila, Stephen A. Rettie, David E. Kim, Daniel-Adriano Silva, Yehia M. Ibrahim, Ian K. Webb, John R. Cort, Joshua N. Adkins, Gabriele Varani, David Baker; Science 2017 (Pubmed)

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Enzyme design and studying​

Isolating conformers to assess dynamics of peptidic catalysts using computationally designed macrocyclic peptides

Elizabeth A. Stone, Parisa Hosseinzadeh​, Timothy W. Craven​, Michael J. Robertson​, Yaodong Han, Sheng-Ying Hsieh, Anthony J. Metrano, David Baker, Scott J. Miller; ACS Catalysis 2021 (Article)

A designed heme-[4Fe-4S] metalloenzyme catalyzes sulfite reduction like the native enzyme

Evan N. Mirts, Igor D. Petrik, Parisa Hosseinzadeh, Mark J. Nilges, Yi Lu; Science 2018 (Article)

Design of a single protein that spans the entire 2-V range of physiological redox potentials

Parisa Hosseinzadeh*, Nicholas M. Marshall*, Kelly N. Chacón, Yang Yu, Mark J. Nilges, Siu Yee New, Stoyan A. Tashkov, Ninian J. Blackburn, Yi Lu; Proc Natl Acad Sci 2016 (Article)